Anti-SSTR5 antibody (1-100) [S6MR] (STJ11102356)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal SSTR5 (1-100) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S6MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SSTR5 |
| Gene ID | 6755 |
| Uniprot ID | SSR5_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MEPLFPASTPSWNASSPGAA SGGGDNRTLVGPAPSAGARA VLVPVLYLLVCAAGLGGNTL VIYVVLRFAKMKTVTNIYIL NLAVADVLYMLGLPFLATQN |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SSTR5 (P35346). |
Additional Info
| Tissue Specificity | Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary. |
| Post Translational Modifications | Palmitoylated by ZDHHC5, but not ZDHHC3, nor ZDHHC8. Palmitoylation creates an additional intracellular loop which is thought to be important for efficient coupling to G-proteins and may target the protein to lipid rafts. |
| Function | Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization. |
| Protein Name | Somatostatin Receptor Type 5Ss-5-RSs5-RSs5rSst5 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Somatostatin Receptor Type 5 antibodyAnti-Ss-5-R antibodyAnti-Ss5-R antibodyAnti-Ss5r antibodyAnti-Sst5 antibodyAnti-SSTR5 antibody |
Information sourced from Uniprot.org