| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SFRS9 (1-221) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SRSF9 |
| Gene ID: |
8683 |
| Uniprot ID: |
SRSF9_HUMAN |
| Immunogen Region: |
1-221 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human SFRS9 (NP_003760.1). |
| Immunogen Sequence: |
MSGWADERGGEGDGRIYVGN LPTDVREKDLEDLFYKYGRI REIELKNRHGLVPFAFVRFE DPRDAEDAIYGRNGYDYGQC RLRVEFPRTYGGRGGWPRGG RNGPPTRRSDFRVLVSGLPP SGSWQDLKDHMREAGDVCYA DVQKDGVGMVEYLRKEDMEY ALRKLDDTKFRSHEGETSYI RVYPERSTSYGYSRSRSGSR GRDSPYQSRGSPHYFSPFRP Y |
| Tissue Specificity | Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle. |
| Post Translational Modifications | Extensively phosphorylated on serine residues in the RS domain. |
| Function | Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10. |
| Protein Name | Serine/Arginine-Rich Splicing Factor 9Pre-Mrna-Splicing Factor Srp30cSplicing Factor - Arginine/Serine-Rich 9 |
| Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856 |
| Cellular Localisation | NucleusCellular Stresses Such As Heat Shock May Induce Localization To Discrete Nuclear Bodies Termed Sam68 Nuclear Bodies (Snbs)Hap BodiesOr Stress BodiesNumerous Splicing Factors Including Srsf1/Sfrs1/Sf2Srsf7/Sfrs7Safb And Khdrbs1/Sam68 Accumulate At These StructuresWhich May Participate In The Post-Transcriptional Regulation Of Mrnas In Stressed Cells |
| Alternative Antibody Names | Anti-Serine/Arginine-Rich Splicing Factor 9 antibodyAnti-Pre-Mrna-Splicing Factor Srp30c antibodyAnti-Splicing Factor - Arginine/Serine-Rich 9 antibodyAnti-SRSF9 antibodyAnti-SFRS9 antibodyAnti-SRP30C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
