| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SRR (1-340) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SRR |
| Gene ID: |
63826 |
| Uniprot ID: |
SRR_HUMAN |
| Immunogen Region: |
1-340 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human SRR (NP_068766.1). |
| Immunogen Sequence: |
MCAQYCISFADVEKAHINIR DSIHLTPVLTSSILNQLTGR NLFFKCELFQKTGSFKIRGA LNAVRSLVPDALERKPKAVV THSSGNHGQALTYAAKLEGI PAYIVVPQTAPDCKKLAIQA YGASIVYCEPSDESRENVAK RVTEETEGIMVHPNQEPAVI AGQGTIALEVLNQVPLVDAL VVPVGGGGMLAGIAITVKAL KPSVKVYAAEPSNADDCYQS KLKGKLMPNLYPPETIADG |
| Tissue Specificity | Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver. |
| Post Translational Modifications | S-nitrosylated, leading to decrease the enzyme activity. |
| Function | Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine. |
| Protein Name | Serine RacemaseD-Serine Ammonia-LyaseD-Serine DehydrataseL-Serine Ammonia-LyaseL-Serine Dehydratase |
| Database Links | Reactome: R-HSA-977347 |
| Alternative Antibody Names | Anti-Serine Racemase antibodyAnti-D-Serine Ammonia-Lyase antibodyAnti-D-Serine Dehydratase antibodyAnti-L-Serine Ammonia-Lyase antibodyAnti-L-Serine Dehydratase antibodyAnti-SRR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Immunofluorescence analysis of HeLa cells using [KO Validated] DNAJB1 Rabbit polyclonal antibody (STJ27455) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/101151/388526/STJ27455_1__36817.1713158040.jpg?c=1 "Immunofluorescence analysis of HeLa cells using [KO Validated] DNAJB1 Rabbit polyclonal antibody (STJ27455) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.")