• Western blot analysis of extracts of various cell lines, using SRR antibody (STJ111657) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
  • Western blot analysis of extracts of various cell lines, using SRR antibody (STJ111657) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-SRR antibody (1-340) (STJ111657)

SKU:
STJ111657

€140.63 - €653.13
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SRR (1-340) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SRR
Gene ID: 63826
Uniprot ID: SRR_HUMAN
Immunogen Region: 1-340
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human SRR (NP_068766.1).
Immunogen Sequence: MCAQYCISFADVEKAHINIR DSIHLTPVLTSSILNQLTGR NLFFKCELFQKTGSFKIRGA LNAVRSLVPDALERKPKAVV THSSGNHGQALTYAAKLEGI PAYIVVPQTAPDCKKLAIQA YGASIVYCEPSDESRENVAK RVTEETEGIMVHPNQEPAVI AGQGTIALEVLNQVPLVDAL VVPVGGGGMLAGIAITVKAL KPSVKVYAAEPSNADDCYQS KLKGKLMPNLYPPETIADG
Tissue Specificity Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.
Post Translational Modifications S-nitrosylated, leading to decrease the enzyme activity.
Function Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Protein Name Serine Racemase
D-Serine Ammonia-Lyase
D-Serine Dehydratase
L-Serine Ammonia-Lyase
L-Serine Dehydratase
Database Links Reactome: R-HSA-977347
Alternative Antibody Names Anti-Serine Racemase antibody
Anti-D-Serine Ammonia-Lyase antibody
Anti-D-Serine Dehydratase antibody
Anti-L-Serine Ammonia-Lyase antibody
Anti-L-Serine Dehydratase antibody
Anti-SRR antibody

Information sourced from Uniprot.org

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