Anti-SRPRB antibody (57-271) (STJ112604)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ112604
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General Information

Short DescriptionRabbit polyclonal SRPRB (57-271) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF/ICC/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:1000-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolSRPRB
Gene ID58477
Uniprot IDSRPRB_HUMAN
Immunogen Region57-271
Immunogen SequenceIRSRRSSQRAVLLVGLCDSG KTLLFVRLLTGLYRDTQTSI TDSCAVYRVNNNRGNSLTLI DLPGHESLRLQFLERFKSSA RAIVFVVDSAAFQREVKDVA EFLYQVLIDSMGLKNTPSFL IACNKQDIAMAKSAKLIQQQ LEKELNTLRVTRSAAPSTLD SSSTAPAQLGKKGKEFEFSQ LPLKVEFLECSAKGGRGDVG SADIQDLEKWLAKIA
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 57-271 of human SRPRB (NP_067026.3).

Additional Info

Function Component of the signal recognition particle (SRP) complex receptor (SR). Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. May mediate the membrane association of SR.
Protein Name Signal Recognition Particle Receptor Subunit Beta
Sr-Beta
Protein Apmcf1
Database Links Reactome: R-HSA-1799339
Reactome: R-HSA-381038
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Signal Recognition Particle Receptor Subunit Beta antibody
Anti-Sr-Beta antibody
Anti-Protein Apmcf1 antibody
Anti-SRPRB antibody
Anti-PSEC0230 antibody

Information sourced from Uniprot.org

Citations

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