| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SRPRB |
| Gene ID: | 58477 |
| Uniprot ID: | SRPRB_HUMAN |
| Immunogen Region: | 57-271 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 57-271 of human SRPRB (NP_067026.3). |
| Immunogen Sequence: | IRSRRSSQRAVLLVGLCDSG KTLLFVRLLTGLYRDTQTSI TDSCAVYRVNNNRGNSLTLI DLPGHESLRLQFLERFKSSA RAIVFVVDSAAFQREVKDVA EFLYQVLIDSMGLKNTPSFL IACNKQDIAMAKSAKLIQQQ LEKELNTLRVTRSAAPSTLD SSSTAPAQLGKKGKEFEFSQ LPLKVEFLECSAKGGRGDVG SADIQDLEKWLAKIA |
| Function | Component of the signal recognition particle (SRP) complex receptor (SR). Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. May mediate the membrane association of SR. |
| Protein Name | Signal Recognition Particle Receptor Subunit Beta Sr-Beta Protein Apmcf1 |
| Database Links | Reactome: R-HSA-1799339 Reactome: R-HSA-381038 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Single-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Signal Recognition Particle Receptor Subunit Beta antibody Anti-Sr-Beta antibody Anti-Protein Apmcf1 antibody Anti-SRPRB antibody Anti-PSEC0230 antibody |
Information sourced from Uniprot.org