Anti-SRI antibody (1-198) (STJ28834)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SRI (1-198) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SRI |
| Gene ID | 6717 |
| Uniprot ID | SORCN_HUMAN |
| Immunogen Region | 1-198 |
| Immunogen Sequence | MAYPGHPGAGGGYYPGGYGG APGGPAFPGQTQDPLYGYFA AVAGQDGQIDADELQRCLTQ SGIAGGYKPFNLETCRLMVS MLDRDMSGTMGFNEFKELWA VLNGWRQHFISFDTDRSGTV DPQELQKALTTMGFRLSPQA VNSIAKRYSTNGKITFDDYI ACCVKLRALTDSFRRRDTAQ QGVVNFPYDDFIQCVMSV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human SRI (NP_003121.1). |
Additional Info
| Tissue Specificity | Detected in cardiac myocytes. |
| Function | Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels. |
| Protein Name | Sorcin22 Kda ProteinCp-22Cp22V19 |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-418359Reactome: R-HSA-425561Reactome: R-HSA-5578775Reactome: R-HSA-936837 |
| Cellular Localisation | CytoplasmSarcoplasmic Reticulum MembranePeripheral Membrane ProteinCytoplasmic SideRelocates To The Sarcoplasmic Reticulum Membrane In Response To Elevated Calcium Levels |
| Alternative Antibody Names | Anti-Sorcin antibodyAnti-22 Kda Protein antibodyAnti-Cp-22 antibodyAnti-Cp22 antibodyAnti-V19 antibodyAnti-SRI antibody |
Information sourced from Uniprot.org