Anti-SRD5A2 antibody (1-100) [S8MR] (STJ11103118)

Name: Anti-SRD5A2 antibody (1-100) [S8MR] (STJ11103118)
SKU: STJ11103118
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11103118

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Short Description	Rabbit monoclonal SRD5A2 (1-100) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S8MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:1000-1:2000 IF/ICC:1:100-1:400 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	SRD5A2
Gene ID	6716
Uniprot ID	S5A2_HUMAN
Immunogen Region	1-100
Immunogen Sequence	MQVQCQQSPVLAGSATLVAL GALALYVAKPSGYGKHTESL KPAATRLPARAAWFLQELPS FAVPAGILARQPLSLFGPPG TVLLGLFCVHYFHRTFVYSL
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRD5A2 (P31213).

Tissue Specificity	Expressed in high levels in the prostate and many other androgen-sensitive tissues.
Function	Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Protein Name	3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2 5 Alpha-Sr2 Sr Type 2 Steroid 5-Alpha-Reductase 2 S5ar 2 Type Ii 5-Alpha Reductase
Database Links	Reactome: R-HSA-193048
Cellular Localisation	Microsome Membrane Multi-Pass Membrane Protein Endoplasmic Reticulum Membrane
Alternative Antibody Names	Anti-3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2 antibody Anti-5 Alpha-Sr2 antibody Anti-Sr Type 2 antibody Anti-Steroid 5-Alpha-Reductase 2 antibody Anti-S5ar 2 antibody Anti-Type Ii 5-Alpha Reductase antibody Anti-SRD5A2 antibody

Information sourced from Uniprot.org