| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-SRD5A2 (1-100) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S8MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SRD5A2 |
| Gene ID: |
6716 |
| Uniprot ID: |
S5A2_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRD5A2 (P31213). |
| Immunogen Sequence: |
MQVQCQQSPVLAGSATLVAL GALALYVAKPSGYGKHTESL KPAATRLPARAAWFLQELPS FAVPAGILARQPLSLFGPPG TVLLGLFCVHYFHRTFVYSL |
| Tissue Specificity | Expressed in high levels in the prostate and many other androgen-sensitive tissues. |
| Function | Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. |
| Protein Name | 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 25 Alpha-Sr2Sr Type 2Steroid 5-Alpha-Reductase 2S5ar 2Type Ii 5-Alpha Reductase |
| Database Links | Reactome: R-HSA-193048 |
| Cellular Localisation | Microsome MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2 antibodyAnti-5 Alpha-Sr2 antibodyAnti-Sr Type 2 antibodyAnti-Steroid 5-Alpha-Reductase 2 antibodyAnti-S5ar 2 antibodyAnti-Type Ii 5-Alpha Reductase antibodyAnti-SRD5A2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Immunoprecipitation analysis of 600 Mu g extracts of 293T cells using 3 Mu g [KD Validated] CDX2 Rabbit monoclonal antibody (STJ11101568). Western blot was performed from the immunoprecipitate using CDX2 antibody (STJ11101568) at a dilution of 1:500.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/90481/359933/STJ11101568_1__84936.1713124490.jpg?c=1 "Immunoprecipitation analysis of 600 Mu g extracts of 293T cells using 3 Mu g [KD Validated] CDX2 Rabbit monoclonal antibody (STJ11101568). Western blot was performed from the immunoprecipitate using CDX2 antibody (STJ11101568) at a dilution of 1:500.")
