| Short Description : | Goat polyclonal antibody anti-SPINT2 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications: | Pep-ELISA/WB |
| Host: | Goat |
| Reactivity: | Human/Rat/Mouse/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Approx 20kDa band observed in Human Placenta lysates (calculated MW of 21.8kDa according to NP_001159575.1). Recommended concentration: 1-3µg/ml. Primary incubation 1 hour at room tempe |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SPINT2 |
| Gene ID: | 10653 |
| Uniprot ID: | SPIT2_HUMAN |
| Accession Number: | NP_066925.1; NP_001159575.1 |
| Immunogen Region: | C-Term |
| Immunogen Sequence: | SGDDKEQLVKNT |
| Specificity: | This antibody is expected to recognize to recognize both reported isoforms (NP_066925.1; NP_001159575.1). |
| Function | Inhibitor of HGFAC. Also inhibits plasmin, and plasma and tissue kallikrein. Inhibits serine protease activity of TMPRSS13. Inhibits serine protease activity of ST14/matriptase and PRSS8/prostasin in vitro. |
| Protein Name | Kunitz-Type Protease Inhibitor 2Hepatocyte Growth Factor Activator Inhibitor Type 2Hai-2Placental Bikunin |
| Database Links | Reactome: R-HSA-6806942Reactome: R-HSA-8852405 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasm |
| Alternative Antibody Names | Anti-Kunitz-Type Protease Inhibitor 2 antibodyAnti-Hepatocyte Growth Factor Activator Inhibitor Type 2 antibodyAnti-Hai-2 antibodyAnti-Placental Bikunin antibodyAnti-SPINT2 antibodyAnti-HAI2 antibodyAnti-KOP antibody |
Information sourced from Uniprot.org
