Anti-SOD1 antibody (40-90 aa) (STJ13100354)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 40-90 of human SOD1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat and mouse.
General Information
| Short Description | Rabbit polyclonal anti-SOD1 (40-90 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1: 3000 is recommended for WB and to 1: 1000 fro IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SOD1 |
| Gene ID | 6647 |
| Uniprot ID | SODC_HUMAN |
| Immunogen | A synthetic peptide from aa region 40-90 of human SOD1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat and mouse. |
| Immunogen Region | 40-90 aa |
| Specificity | Specific for SOD1. |
Additional Info
| Function | Destroys radicals which are normally produced within the cells and which are toxic to biological systems. |
| Protein Name | Superoxide Dismutase Cu-ZnSuperoxide Dismutase 1Hsod1 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-3299685Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicThe Pathogenic Variants Als1 Arg-86 And Ala-94 Gradually Aggregates And Accumulates In Mitochondria |
| Alternative Antibody Names | Anti-Superoxide Dismutase Cu-Zn antibodyAnti-Superoxide Dismutase 1 antibodyAnti-Hsod1 antibodyAnti-SOD1 antibody |
Information sourced from Uniprot.org