| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SOD1 (40-90 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1: 3000 is recommended for WB and to 1: 1000 fro IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SOD1 |
| Gene ID: | 6647 |
| Uniprot ID: | SODC_HUMAN |
| Immunogen Region: | 40-90 aa |
| Specificity: | Specific for SOD1. |
| Immunogen: | A synthetic peptide from aa region 40-90 of human SOD1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat and mouse. |
| Function | Destroys radicals which are normally produced within the cells and which are toxic to biological systems. |
| Protein Name | Superoxide Dismutase Cu-ZnSuperoxide Dismutase 1Hsod1 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-3299685Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicThe Pathogenic Variants Als1 Arg-86 And Ala-94 Gradually Aggregates And Accumulates In Mitochondria |
| Alternative Antibody Names | Anti-Superoxide Dismutase Cu-Zn antibodyAnti-Superoxide Dismutase 1 antibodyAnti-Hsod1 antibodyAnti-SOD1 antibody |
Information sourced from Uniprot.org