• Immunohistochemistry analysis of SNRPB in paraffin-embedded mouse spleen using SNRPB Rabbit polyclonal antibody (STJ116166) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of SNRPB in paraffin-embedded human colon carcinoma using SNRPB Rabbit polyclonal antibody (STJ116166) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of SNRPB in paraffin-embedded rat spleen using SNRPB Rabbit polyclonal antibody (STJ116166) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using SNRPB Rabbit polyclonal antibody (STJ116166) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.

Anti-SNRPB antibody (1-100) (STJ116166)

SKU:
STJ116166

€140.63 - €653.13
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SNRPB (1-100) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SNRPB
Gene ID: 6628
Uniprot ID: RSMB_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SNRPB (NP_003082.1).
Immunogen Sequence: MTVGKSSKMLQHIDYRMRCI LQDGRIFIGTFKAFDKHMNL ILCDCDEFRKIKPKNSKQAE REEKRVLGLVLLRGENLVSM TVEGPPPKDTGIARVPLAGA
Post Translational Modifications Methylated by PRMT5. Arg-108 and Arg-112 are dimethylated, probably to asymmetric dimethylarginine.
Function Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
Protein Name Small Nuclear Ribonucleoprotein-Associated Proteins B And B'
Snrnp-B
Sm Protein B/B'
Sm-B/B'
Smb/B'
Database Links Reactome: R-HSA-111367
Reactome: R-HSA-191859
Reactome: R-HSA-72163
Reactome: R-HSA-72165
Reactome: R-HSA-73856
Reactome: R-HSA-77588
Reactome: R-HSA-9754678
Cellular Localisation Cytoplasm
Cytosol
Nucleus
Smn-Mediated Assembly Into Core Snrnps Occurs In The Cytosol Before Smn-Mediated Transport To The Nucleus To Be Included In Spliceosomes
Alternative Antibody Names Anti-Small Nuclear Ribonucleoprotein-Associated Proteins B And B' antibody
Anti-Snrnp-B antibody
Anti-Sm Protein B/B' antibody
Anti-Sm-B/B' antibody
Anti-Smb/B' antibody
Anti-SNRPB antibody
Anti-COD antibody
Anti-SNRPB1 antibody

Information sourced from Uniprot.org

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