Anti-SNAP29 antibody (1-258) (STJ25638)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SNAP29 (1-258) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SNAP29 |
| Gene ID | 9342 |
| Uniprot ID | SNP29_HUMAN |
| Immunogen Region | 1-258 |
| Immunogen Sequence | MSAYPKSYNPFDDDGEDEGA RPAPWRDARDLPDGPDAPAD RQQYLRQEVLRRAEATAAST SRSLALMYESEKVGVASSEE LARQRGVLERTEKMVDKMDQ DLKISQKHINSIKSVFGGLV NYFKSKPVETPPEQNGTLTS QPNNRLKEAISTSKEQEAKY QASHPNLRKLDDTDPVPRGA GSAMSTDAYPKNPHLRAYHQ KIDSNLDELSMGLGRLKDIA LGMQTEIEEQDDILDRLTT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-258 of human SNAP29 (NP_004773.1). |
Additional Info
| Tissue Specificity | Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. |
| Function | SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions. |
| Protein Name | Synaptosomal-Associated Protein 29Snap-29Soluble 29 Kda Nsf Attachment ProteinVesicle-Membrane Fusion Protein Snap-29 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6811438 |
| Cellular Localisation | CytoplasmGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic VesicleAutophagosome MembraneCell ProjectionCilium MembraneAppears To Be Mostly Membrane-BoundProbably Via Interaction With SyntaxinsBut A Significant Portion Is CytoplasmicLocalizes To The Ciliary Pocket From Where The Cilium Protrudes |
| Alternative Antibody Names | Anti-Synaptosomal-Associated Protein 29 antibodyAnti-Snap-29 antibodyAnti-Soluble 29 Kda Nsf Attachment Protein antibodyAnti-Vesicle-Membrane Fusion Protein Snap-29 antibodyAnti-SNAP29 antibody |
Information sourced from Uniprot.org