Anti-SMARCD2 antibody (STJA0009163)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SMARCD2
General Information
| Short Description | Rabbit polyclonal anti-SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SMARCD2 |
| Gene ID | 6603 |
| Uniprot ID | SMRD2_HUMAN |
| Immunogen | Synthesized peptide derived from human SMARCD2 |
| Specificity | This antibody detects endogenous levels of SMARCD2 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Ubiquitinated through a signaling process involving RAC1 and the RING finger protein UNKL. |
| Function | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation. |
| Protein Name | Swi/Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily D Member 260 Kda Brg-1/Brm-Associated Factor Subunit BBrg1-Associated Factor 60bBaf60b |
| Database Links | Reactome: R-HSA-3214858Reactome: R-HSA-8939243Reactome: R-HSA-9824585Reactome: R-HSA-9845323 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Swi/Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily D Member 2 antibodyAnti-60 Kda Brg-1/Brm-Associated Factor Subunit B antibodyAnti-Brg1-Associated Factor 60b antibodyAnti-Baf60b antibodyAnti-SMARCD2 antibodyAnti-BAF60B antibodyAnti-PRO2451 antibody |
Information sourced from Uniprot.org