| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SMARCD2 |
| Gene ID: |
6603 |
| Uniprot ID: |
SMRD2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of SMARCD2 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human SMARCD2 |
| Post Translational Modifications | Ubiquitinated through a signaling process involving RAC1 and the RING finger protein UNKL. |
| Function | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation. |
| Protein Name | Swi/Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily D Member 260 Kda Brg-1/Brm-Associated Factor Subunit BBrg1-Associated Factor 60bBaf60b |
| Database Links | Reactome: R-HSA-3214858Reactome: R-HSA-8939243 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Swi/Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily D Member 2 antibodyAnti-60 Kda Brg-1/Brm-Associated Factor Subunit B antibodyAnti-Brg1-Associated Factor 60b antibodyAnti-Baf60b antibodyAnti-SMARCD2 antibodyAnti-BAF60B antibodyAnti-PRO2451 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
