Anti-SLC8A2 antibody (360-450) (STJ118169)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC8A2 (360-450) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC8A2 |
| Gene ID | 6543 |
| Uniprot ID | NAC2_HUMAN |
| Immunogen Region | 360-450 |
| Immunogen Sequence | LMTGAGNVLRRHAADASRRA APAEGAGEDEDDGASRIFFE PSLYHCLENCGSVLLSVTCQ GGEGNSTFYVDYRTEDGSAK AGSDYEYSEGT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 360-450 of human SLC8A2 (NP_055878.1). |
Additional Info
| Function | Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca(2+) and Na(+) excretion. |
| Protein Name | Sodium/Calcium Exchanger 2Na(+/Ca(2+-Exchange Protein 2Solute Carrier Family 8 Member 2 |
| Database Links | Reactome: R-HSA-418359Reactome: R-HSA-425561Reactome: R-HSA-5578775 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembranePerikaryonCell ProjectionDendriteDendritic Spine |
| Alternative Antibody Names | Anti-Sodium/Calcium Exchanger 2 antibodyAnti-Na(+/Ca(2+-Exchange Protein 2 antibodyAnti-Solute Carrier Family 8 Member 2 antibodyAnti-SLC8A2 antibodyAnti-KIAA1087 antibodyAnti-NCX2 antibody |
Information sourced from Uniprot.org