Anti-SLC8A2 antibody (360-450) (STJ118169)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ118169
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General Information

Short DescriptionRabbit polyclonal SLC8A2 (360-450) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolSLC8A2
Gene ID6543
Uniprot IDNAC2_HUMAN
Immunogen Region360-450
Immunogen SequenceLMTGAGNVLRRHAADASRRA APAEGAGEDEDDGASRIFFE PSLYHCLENCGSVLLSVTCQ GGEGNSTFYVDYRTEDGSAK AGSDYEYSEGT
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 360-450 of human SLC8A2 (NP_055878.1).

Additional Info

Function Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca(2+) and Na(+) excretion.
Protein Name Sodium/Calcium Exchanger 2
Na(+/Ca(2+-Exchange Protein 2
Solute Carrier Family 8 Member 2
Database Links Reactome: R-HSA-418359
Reactome: R-HSA-425561
Reactome: R-HSA-5578775
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Perikaryon
Cell Projection
Dendrite
Dendritic Spine
Alternative Antibody Names Anti-Sodium/Calcium Exchanger 2 antibody
Anti-Na(+/Ca(2+-Exchange Protein 2 antibody
Anti-Solute Carrier Family 8 Member 2 antibody
Anti-SLC8A2 antibody
Anti-KIAA1087 antibody
Anti-NCX2 antibody

Information sourced from Uniprot.org

Citations

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