Western blot analysis of various lysates, using SLC6A2 Rabbit monoclonal antibody (STJ11104951) at 1:16000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-SLC6A2 antibody (1-70) [S4951RM] (STJ11104951)

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STJ11104951
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Applications:WB/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :S4951RM
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:2000-1:10000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:SLC6A2
Gene ID:6530
Uniprot ID:SC6A2_HUMAN
Immunogen Region:1-70
Immunogen Sequence:MLLARMNPQVQPENNGADTG PEQPLRARKTAELLVVKERN GVQCLLAPRDGDAQPRETWG KKIDFLLSVV
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human SLC6A2 (NP_001034.1).
Post Translational Modifications Palmitoylated.palmitoylation regulates protein levels and neurotransmitter transport.
Function Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline), the primary signaling neurotransmitter in the autonomic sympathetic nervous system. Is responsible for norepinephrine re-uptake and clearance from the synaptic cleft, thus playing a crucial role in norepinephrine inactivation and homeostasis. Can also mediate sodium- and chloride-dependent transport of dopamine.
Protein Name Sodium-Dependent Noradrenaline Transporter
Norepinephrine Transporter
Net
Solute Carrier Family 6 Member 2
Database Links Reactome: R-HSA-442660
Reactome: R-HSA-5619109
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Axon
Synapse
Synaptosome
Alternative Antibody Names Anti-Sodium-Dependent Noradrenaline Transporter antibody
Anti-Norepinephrine Transporter antibody
Anti-Net antibody
Anti-Solute Carrier Family 6 Member 2 antibody
Anti-SLC6A2 antibody
Anti-NAT1 antibody
Anti-NET1 antibody
Anti-SLC6A5 antibody

Information sourced from Uniprot.org

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