Anti-SLC6A14 antibody (131-234) (STJ112596)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC6A14 (131-234) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC6A14 |
| Gene ID | 11254 |
| Uniprot ID | S6A14_HUMAN |
| Immunogen Region | 131-234 |
| Immunogen Sequence | YYNVIIAYSLYYMFASFQSE LPWKNCSSWSDKNCSRSPIV THCNVSTVNKGIQEIIQMNK SWVDINNFTCINGSEIYQPG QLPSEQYWNKVALQRSSGMN ETGV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 131-234 of human SLC6A14 (NP_009162.1). |
Additional Info
| Tissue Specificity | Levels are highest in adult and fetal lung, in trachea and salivary gland. Lower levels detected in mammary gland, stomach and pituitary gland, and very low levels in colon, uterus, prostate and testis. |
| Function | Amino acid transporter that plays an important role in the absorption of amino acids in the intestinal tract. Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner. Transports non-alpha-amino acids such as beta-alanine with low affinity, and has a higher affinity for dipolar and cationic amino acids such as leucine and lysine. Can also transport carnitine, butirylcarnitine and propionylcarnitine coupled to the transmembrane gradients of Na(+) and Cl(-). |
| Protein Name | Sodium- And Chloride-Dependent Neutral And Basic Amino Acid Transporter B(0+Amino Acid Transporter Atb0+Solute Carrier Family 6 Member 14 |
| Database Links | Reactome: R-HSA-352230Reactome: R-HSA-442660Reactome: R-HSA-5619094 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Sodium- And Chloride-Dependent Neutral And Basic Amino Acid Transporter B(0+ antibodyAnti-Amino Acid Transporter Atb0+ antibodyAnti-Solute Carrier Family 6 Member 14 antibodyAnti-SLC6A14 antibody |
Information sourced from Uniprot.org