• Western blot analysis of extracts of various cell lines, using SLC6A14 antibody (STJ112596) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-SLC6A14 antibody (131-234) (STJ112596)

SKU:
STJ112596

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SLC6A14 (131-234) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC6A14
Gene ID: 11254
Uniprot ID: S6A14_HUMAN
Immunogen Region: 131-234
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 131-234 of human SLC6A14 (NP_009162.1).
Immunogen Sequence: YYNVIIAYSLYYMFASFQSE LPWKNCSSWSDKNCSRSPIV THCNVSTVNKGIQEIIQMNK SWVDINNFTCINGSEIYQPG QLPSEQYWNKVALQRSSGMN ETGV
Tissue Specificity Levels are highest in adult and fetal lung, in trachea and salivary gland. Lower levels detected in mammary gland, stomach and pituitary gland, and very low levels in colon, uterus, prostate and testis.
Function Amino acid transporter that plays an important role in the absorption of amino acids in the intestinal tract. Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner. Transports non-alpha-amino acids such as beta-alanine with low affinity, and has a higher affinity for dipolar and cationic amino acids such as leucine and lysine. Can also transport carnitine, butirylcarnitine and propionylcarnitine coupled to the transmembrane gradients of Na(+) and Cl(-).
Protein Name Sodium- And Chloride-Dependent Neutral And Basic Amino Acid Transporter B(0+
Amino Acid Transporter Atb0+
Solute Carrier Family 6 Member 14
Database Links Reactome: R-HSA-352230
Reactome: R-HSA-442660
Reactome: R-HSA-5619094
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Apical Cell Membrane
Alternative Antibody Names Anti-Sodium- And Chloride-Dependent Neutral And Basic Amino Acid Transporter B(0+ antibody
Anti-Amino Acid Transporter Atb0+ antibody
Anti-Solute Carrier Family 6 Member 14 antibody
Anti-SLC6A14 antibody

Information sourced from Uniprot.org

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