| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC5A12 (200-280) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC5A12 |
| Gene ID: |
159963 |
| Uniprot ID: |
SC5AC_HUMAN |
| Immunogen Region: |
200-280 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 200-280 of human SLC5A12 (NP_848593.2). |
| Immunogen Sequence: |
LIQGSTHAGGFHNVLEQSTN GSRLHIFDFDVDPLRRHTFW TITVGGTFTWLGIYGVNQST IQRCISCKTEKHAKLALYFN L |
| Function | Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina. |
| Protein Name | Sodium-Coupled Monocarboxylate Transporter 2Electroneutral Sodium Monocarboxylate CotransporterLow-Affinity Sodium-Lactate CotransporterSolute Carrier Family 5 Member 12 |
| Database Links | Reactome: R-HSA-427601 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinDetected At The Brush Border Membrane Of The KidneyColocalizes With Viementin In Mueller Cells |
| Alternative Antibody Names | Anti-Sodium-Coupled Monocarboxylate Transporter 2 antibodyAnti-Electroneutral Sodium Monocarboxylate Cotransporter antibodyAnti-Low-Affinity Sodium-Lactate Cotransporter antibodyAnti-Solute Carrier Family 5 Member 12 antibodyAnti-SLC5A12 antibodyAnti-SMCT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
