Anti-SLC5A12 antibody (200-280) (STJ118617)

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STJ118617
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Short Description :Rabbit polyclonal SLC5A12 (200-280) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:SLC5A12
Gene ID:159963
Uniprot ID:SC5AC_HUMAN
Immunogen Region:200-280
Immunogen Sequence:LIQGSTHAGGFHNVLEQSTN GSRLHIFDFDVDPLRRHTFW TITVGGTFTWLGIYGVNQST IQRCISCKTEKHAKLALYFN L
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 200-280 of human SLC5A12 (NP_848593.2).
Function Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina.
Protein Name Sodium-Coupled Monocarboxylate Transporter 2
Electroneutral Sodium Monocarboxylate Cotransporter
Low-Affinity Sodium-Lactate Cotransporter
Solute Carrier Family 5 Member 12
Database Links Reactome: R-HSA-427601
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Detected At The Brush Border Membrane Of The Kidney
Colocalizes With Viementin In Mueller Cells
Alternative Antibody Names Anti-Sodium-Coupled Monocarboxylate Transporter 2 antibody
Anti-Electroneutral Sodium Monocarboxylate Cotransporter antibody
Anti-Low-Affinity Sodium-Lactate Cotransporter antibody
Anti-Solute Carrier Family 5 Member 12 antibody
Anti-SLC5A12 antibody
Anti-SMCT2 antibody

Information sourced from Uniprot.org