| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC32A1 (1-525) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC32A1 |
| Gene ID: |
140679 |
| Uniprot ID: |
VIAAT_HUMAN |
| Immunogen Region: |
1-525 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-525 of human SLC32A1 (Q9H598). |
| Immunogen Sequence: |
MATLLRSKLSNVATSVSNKS QAKMSGMFARMGFQAATDEE AVGFAHCDDLDFEHRQGLQM DILKAEGEPCGDEGAEAPVE GDIHYQRGSGAPLPPSGSKD QVGGGGEFGGHDKPKITAWE AGWNVTNAIQGMFVLGLPYA ILHGGYLGLFLIIFAAVVCC YTGKILIACLYEENEDGEVV RVRDSYVAIANACCAPRFPT LGGRVVNVAQIIELVMTCIL YVVVSGNLMYNSFPGLPVS |
| Tissue Specificity | Retina. Expressed throughout the horizontal cells or more specifically at the terminals. |
| Function | Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient. May also transport beta-alanine. Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake. |
| Protein Name | Vesicular Inhibitory Amino Acid TransporterGaba And Glycine TransporterSolute Carrier Family 32 Member 1Vesicular Gaba TransporterHviaat |
| Database Links | Reactome: R-HSA-425393Reactome: R-HSA-888590 |
| Cellular Localisation | Cytoplasmic Vesicle MembraneMulti-Pass Membrane ProteinPresynapsePresents In Glycine-Gaba- Or Gaba- And Glycine-Containing Boutons |
| Alternative Antibody Names | Anti-Vesicular Inhibitory Amino Acid Transporter antibodyAnti-Gaba And Glycine Transporter antibodyAnti-Solute Carrier Family 32 Member 1 antibodyAnti-Vesicular Gaba Transporter antibodyAnti-Hviaat antibodyAnti-SLC32A1 antibodyAnti-VGAT antibodyAnti-VIAAT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
