Anti-SLC32A1 antibody (1-525) (STJ25579)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC32A1 (1-525) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC32A1 |
| Gene ID | 140679 |
| Uniprot ID | VIAAT_HUMAN |
| Immunogen Region | 1-525 |
| Immunogen Sequence | MATLLRSKLSNVATSVSNKS QAKMSGMFARMGFQAATDEE AVGFAHCDDLDFEHRQGLQM DILKAEGEPCGDEGAEAPVE GDIHYQRGSGAPLPPSGSKD QVGGGGEFGGHDKPKITAWE AGWNVTNAIQGMFVLGLPYA ILHGGYLGLFLIIFAAVVCC YTGKILIACLYEENEDGEVV RVRDSYVAIANACCAPRFPT LGGRVVNVAQIIELVMTCIL YVVVSGNLMYNSFPGLPVS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-525 of human SLC32A1 (Q9H598). |
Additional Info
| Tissue Specificity | Retina. Expressed throughout the horizontal cells or more specifically at the terminals. |
| Function | Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient. May also transport beta-alanine. Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake. |
| Protein Name | Vesicular Inhibitory Amino Acid TransporterGaba And Glycine TransporterSolute Carrier Family 32 Member 1Vesicular Gaba TransporterHviaat |
| Database Links | Reactome: R-HSA-425393Reactome: R-HSA-888590 |
| Cellular Localisation | Cytoplasmic Vesicle MembraneMulti-Pass Membrane ProteinPresynapsePresents In Glycine-Gaba- Or Gaba- And Glycine-Containing Boutons |
| Alternative Antibody Names | Anti-Vesicular Inhibitory Amino Acid Transporter antibodyAnti-Gaba And Glycine Transporter antibodyAnti-Solute Carrier Family 32 Member 1 antibodyAnti-Vesicular Gaba Transporter antibodyAnti-Hviaat antibodyAnti-SLC32A1 antibodyAnti-VGAT antibodyAnti-VIAAT antibody |
Information sourced from Uniprot.org