| Tissue Specificity | Ubiquitous with high expression in placenta and heart. |
| Post Translational Modifications | Ubiquitinated.ubiquitination and the subsequent proteasomal degradation are prevent by SLC31A1 that stabilizes it. |
| Function | Does not function as a copper(1+) importer in vivo. However, in vitro functions as a low-affinity copper(1+) importer. Regulator of SLC31A1 which facilitates the cleavage of the SLC31A1 ecto-domain or which stabilizes the truncated form of SLC31A1 (Truncated CTR1 form), thereby drives the SLC31A1 truncated form-dependent endosomal copper export and modulates the copper and cisplatin accumulation via SLC31A1. |
| Protein Name | Protein Slc31a2Copper Transporter 2Hctr2Solute Carrier Family 31 Member 2 |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembraneLate Endosome MembraneLysosome MembranePlasma Membrane Localization Is Partial |
| Alternative Antibody Names | Anti-Protein Slc31a2 antibodyAnti-Copper Transporter 2 antibodyAnti-Hctr2 antibodyAnti-Solute Carrier Family 31 Member 2 antibodyAnti-SLC31A2 antibodyAnti-COPT2 antibodyAnti-CTR2 antibody |
Information sourced from Uniprot.org
