Anti-Slc31a2 antibody (1-100) (STJ118790)

Name: Anti-Slc31a2 antibody (1-100) (STJ118790)
SKU: STJ118790
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ118790

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Short Description	Rabbit polyclonal Slc31a2 (1-100) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	SLC31A2
Gene ID	1318
Uniprot ID	COPT2_HUMAN
Immunogen Region	1-100
Immunogen Sequence	MHFIFSDEAVLLFDFWRVHS PTGMALSVLVVLLLAVLYEG IKVGKAKLLHKTLESLPATN SQQFILGPDQDSTGSRSTSD NRTRLRWFLCYFGQSLVHVI
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of mouse Slc31a2 (NP_001277447.1).

Tissue Specificity	Ubiquitous with high expression in placenta and heart.
Post Translational Modifications	Ubiquitinated.ubiquitination and the subsequent proteasomal degradation are prevent by SLC31A1 that stabilizes it.
Function	Does not function as a copper(1+) importer in vivo. However, in vitro functions as a low-affinity copper(1+) importer. Regulator of SLC31A1 which facilitates the cleavage of the SLC31A1 ecto-domain or which stabilizes the truncated form of SLC31A1 (Truncated CTR1 form), thereby drives the SLC31A1 truncated form-dependent endosomal copper export and modulates the copper and cisplatin accumulation via SLC31A1.
Protein Name	Protein Slc31a2 Copper Transporter 2 Hctr2 Solute Carrier Family 31 Member 2
Database Links
Cellular Localisation	Membrane Multi-Pass Membrane Protein Cytoplasmic Vesicle Membrane Late Endosome Membrane Lysosome Membrane Plasma Membrane Localization Is Partial
Alternative Antibody Names	Anti-Protein Slc31a2 antibody Anti-Copper Transporter 2 antibody Anti-Hctr2 antibody Anti-Solute Carrier Family 31 Member 2 antibody Anti-SLC31A2 antibody Anti-COPT2 antibody Anti-CTR2 antibody

Information sourced from Uniprot.org