| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Anion exchange transporter (595-645 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC26A7 |
| Gene ID: |
115111 |
| Uniprot ID: |
S26A7_HUMAN |
| Immunogen Region: |
595-645 aa |
| Specificity: |
This antibody detects endogenous levels of S26A7 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human S26A7 at the amino acid range 595-645 |
| Function | Acts as an anion channel mediating the transport of chloride, sulfate and oxalate ions. Mediates the transport of bromide, iodide, nitrate, gluconate, thiocyanate and bicarbonate ions. Its permeability towards bicarbonate is weak and increases when pH is above 7. Mediates thiocyanate transport in retinal pigment epithelium cells. Mediates iodide transport in the thyroid gland, playing an important role in the synthesis of thyroid hormones and the maintenance of thyroid function. Although it is an anion channel, it has been shown to exhibit chloride-bicarbonate exchanger activity. |
| Protein Name | Anion Exchange TransporterSolute Carrier Family 26 Member 7 |
| Database Links | Reactome: R-HSA-427601 |
| Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane ProteinRecycling Endosome MembraneApical Cell MembraneLateral Cell MembraneExpressed In The Cytoplasm In Recycling Endosomes Of Medullary Collecting Duct Cells And In Acid-Secreting Gastric Parietal CellsTargeted To The Basolateral Membrane In Hypertonicity And Potassium Depletion |
| Alternative Antibody Names | Anti-Anion Exchange Transporter antibodyAnti-Solute Carrier Family 26 Member 7 antibodyAnti-SLC26A7 antibodyAnti-SUT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
