| Function | Acts as an anion channel mediating the transport of chloride, sulfate and oxalate ions. Mediates the transport of bromide, iodide, nitrate, gluconate, thiocyanate and bicarbonate ions. Its permeability towards bicarbonate is weak and increases when pH is above 7. Mediates thiocyanate transport in retinal pigment epithelium cells. Mediates iodide transport in the thyroid gland, playing an important role in the synthesis of thyroid hormones and the maintenance of thyroid function. Although it is an anion channel, it has been shown to exhibit chloride-bicarbonate exchanger activity. |
| Protein Name | Anion Exchange TransporterSolute Carrier Family 26 Member 7 |
| Database Links | Reactome: R-HSA-427601 |
| Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane ProteinRecycling Endosome MembraneApical Cell MembraneLateral Cell MembraneExpressed In The Cytoplasm In Recycling Endosomes Of Medullary Collecting Duct Cells And In Acid-Secreting Gastric Parietal CellsTargeted To The Basolateral Membrane In Hypertonicity And Potassium Depletion |
| Alternative Antibody Names | Anti-Anion Exchange Transporter antibodyAnti-Solute Carrier Family 26 Member 7 antibodyAnti-SLC26A7 antibodyAnti-SUT2 antibody |
Information sourced from Uniprot.org
