| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC26A11 (500-600) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC26A11 |
| Gene ID: |
284129 |
| Uniprot ID: |
S2611_HUMAN |
| Immunogen Region: |
500-600 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 500-600 of human SLC26A11 (NP_001159819.1). |
| Immunogen Sequence: |
EILSRALEVSPPRCLVLECT HVCSIDYTVVLGLGELLQDF QKQGVALAFVGLQVPVLRVL LSADLKGFQYFSTLEEAEKH LRQEPGTQPYNIREDSILDQ K |
| Tissue Specificity | Detected in all tissues tested with highest expression observed in brain, kidney, HEVEC and placenta and lowest in pancreas, skeletal muscle, liver, lung and heart. |
| Function | Sodium-independent anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). In the kidney, mediates chloride-bicarbonate exchange, facilitating V-ATPase-mediated acid secretion. May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum. |
| Protein Name | Sodium-Independent Sulfate Anion TransporterSolute Carrier Family 26 Member 11 |
| Database Links | Reactome: R-HSA-427601 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLysosome MembraneApical Cell MembraneBasolateral Cell Membrane |
| Alternative Antibody Names | Anti-Sodium-Independent Sulfate Anion Transporter antibodyAnti-Solute Carrier Family 26 Member 11 antibodyAnti-SLC26A11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
