Western blot analysis of various lysates using SLC26A11 Rabbit polyclonal antibody (STJ119420) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-SLC26A11 antibody (500-600) (STJ119420)

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STJ119420
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Short Description :Rabbit polyclonal SLC26A11 (500-600) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:SLC26A11
Gene ID:284129
Uniprot ID:S2611_HUMAN
Immunogen Region:500-600
Immunogen Sequence:EILSRALEVSPPRCLVLECT HVCSIDYTVVLGLGELLQDF QKQGVALAFVGLQVPVLRVL LSADLKGFQYFSTLEEAEKH LRQEPGTQPYNIREDSILDQ K
Specificity:A synthetic peptide corresponding to a sequence within amino acids 500-600 of human SLC26A11 (NP_001159819.1).
Tissue Specificity Detected in all tissues tested with highest expression observed in brain, kidney, HEVEC and placenta and lowest in pancreas, skeletal muscle, liver, lung and heart.
Function Sodium-independent anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). In the kidney, mediates chloride-bicarbonate exchange, facilitating V-ATPase-mediated acid secretion. May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum.
Protein Name Sodium-Independent Sulfate Anion Transporter
Solute Carrier Family 26 Member 11
Database Links Reactome: R-HSA-427601
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Lysosome Membrane
Apical Cell Membrane
Basolateral Cell Membrane
Alternative Antibody Names Anti-Sodium-Independent Sulfate Anion Transporter antibody
Anti-Solute Carrier Family 26 Member 11 antibody
Anti-SLC26A11 antibody

Information sourced from Uniprot.org

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