Anti-SLC25A38 antibody (1-304) (STJ115184)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC25A38 (1-304) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC25A38 |
| Gene ID | 54977 |
| Uniprot ID | S2538_HUMAN |
| Immunogen Region | 1-304 |
| Immunogen Sequence | MIQNSRPSLLQPQDVGDTVE TLMLHPVIKAFLCGSISGTC STLLFQPLDLLKTRLQTLQP SDHGSRRVGMLAVLLKVVRT ESLLGLWKGMSPSIVRCVPG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC25A38 (NP_060345.2). |
Additional Info
| Tissue Specificity | Preferentially expressed in erythroid cells. |
| Function | Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis. Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis. |
| Protein Name | Mitochondrial Glycine TransporterAppoptosinMitochondrial Glycine Transporter GlycSolute Carrier Family 25 Member 38 |
| Database Links | |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Glycine Transporter antibodyAnti-Appoptosin antibodyAnti-Mitochondrial Glycine Transporter Glyc antibodyAnti-Solute Carrier Family 25 Member 38 antibodyAnti-SLC25A38 antibody |
Information sourced from Uniprot.org