Anti-SLC25A20 antibody (40-55) (STJ115891)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC25A20 (40-55) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC25A20 |
| Gene ID | 788 |
| Uniprot ID | MCAT_HUMAN |
| Immunogen Region | 40-55 |
| Immunogen Sequence | MADQPKPISPLKNLLAGGFG GVCLVFVGHPLDTVKVRLQT QPPSLPGQPPMYSGTFDCFR KTLFREGITGLYRGMAAPII GVTPMFAVCFFGFGLGKKLQ |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC25A20 (NP_000378.1). |
Additional Info
| Function | Mediates the electroneutral exchange of acylcarnitines (O-acyl-(R)-carnitine or L-acylcarnitine) of different acyl chain lengths (ranging from O-acetyl-(R)-carnitine to long-chain O-acyl-(R)-carnitines) with free carnitine ((R)-carnitine or L-carnitine) across the mitochondrial inner membrane, via a ping-pong mechanism (Probable). Key player in the mitochondrial oxidation pathway, it translocates the fatty acids in the form of acylcarnitines into the mitochondrial matrix, where the carnitine palmitoyltransferase 2 (CPT-2) activates them to undergo fatty acid beta-oxidation (Probable). Catalyzes the unidirectional transport (uniport) of carnitine at lower rates than the antiport (exchange). |
| Protein Name | Mitochondrial Carnitine/Acylcarnitine Carrier ProteinCarnitine/Acylcarnitine TranslocaseCacCactSolute Carrier Family 25 Member 20 |
| Database Links | Reactome: R-HSA-200425 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Carnitine/Acylcarnitine Carrier Protein antibodyAnti-Carnitine/Acylcarnitine Translocase antibodyAnti-Cac antibodyAnti-Cact antibodyAnti-Solute Carrier Family 25 Member 20 antibodyAnti-SLC25A20 antibodyAnti-CAC antibodyAnti-CACT antibody |
Information sourced from Uniprot.org