Anti-SLC16A2 antibody (1-100) (STJ116209)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC16A2 (1-100) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC16A2 |
| Gene ID | 6567 |
| Uniprot ID | MOT8_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MALQSQASEEAKGPWQEADQ EQQEPVGSPEPESEPEPEPE PEPVPVPPPEPQPEPQPLPD PAPLPELEFESERVHEPEPT PTVETRGTARGFQPPEGGFG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC16A2 (NP_006508.2). |
Additional Info
| Tissue Specificity | Highly expressed in liver and heart. In adult brain tissue expression is largely confined to endothelial cells of the blood-brain barrier (at protein level). |
| Function | Specific thyroid hormone transmembrane transporter, that mediates both uptake and efflux of thyroid hormones across the cell membrane independently of pH or a Na(+) gradient. Major substrates are the iodothyronines T3 and T4 and to a lesser extent rT3 and 3,3-diiodothyronine (3,3'-T2). Acts as an important mediator of thyroid hormone transport, especially T3, through the blood-brain barrier (Probable). |
| Protein Name | Monocarboxylate Transporter 8Mct 8Monocarboxylate Transporter 7Mct 7Solute Carrier Family 16 Member 2X-Linked Pest-Containing Transporter |
| Database Links | Reactome: R-HSA-879518 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Monocarboxylate Transporter 8 antibodyAnti-Mct 8 antibodyAnti-Monocarboxylate Transporter 7 antibodyAnti-Mct 7 antibodyAnti-Solute Carrier Family 16 Member 2 antibodyAnti-X-Linked Pest-Containing Transporter antibodyAnti-SLC16A2 antibodyAnti-MCT7 antibodyAnti-MCT8 antibodyAnti-XPCT antibody |
Information sourced from Uniprot.org