| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC16A2 (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC16A2 |
| Gene ID: |
6567 |
| Uniprot ID: |
MOT8_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC16A2 (NP_006508.2). |
| Immunogen Sequence: |
MALQSQASEEAKGPWQEADQ EQQEPVGSPEPESEPEPEPE PEPVPVPPPEPQPEPQPLPD PAPLPELEFESERVHEPEPT PTVETRGTARGFQPPEGGFG |
| Tissue Specificity | Highly expressed in liver and heart. In adult brain tissue expression is largely confined to endothelial cells of the blood-brain barrier (at protein level). |
| Function | Specific thyroid hormone transmembrane transporter, that mediates both uptake and efflux of thyroid hormones across the cell membrane independently of pH or a Na(+) gradient. Major substrates are the iodothyronines T3 and T4 and to a lesser extent rT3 and 3,3-diiodothyronine (3,3'-T2). Acts as an important mediator of thyroid hormone transport, especially T3, through the blood-brain barrier (Probable). |
| Protein Name | Monocarboxylate Transporter 8Mct 8Monocarboxylate Transporter 7Mct 7Solute Carrier Family 16 Member 2X-Linked Pest-Containing Transporter |
| Database Links | Reactome: R-HSA-879518 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Monocarboxylate Transporter 8 antibodyAnti-Mct 8 antibodyAnti-Monocarboxylate Transporter 7 antibodyAnti-Mct 7 antibodyAnti-Solute Carrier Family 16 Member 2 antibodyAnti-X-Linked Pest-Containing Transporter antibodyAnti-SLC16A2 antibodyAnti-MCT7 antibodyAnti-MCT8 antibodyAnti-XPCT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
