| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Solute carrier family 13 member 2/dicarboxylate cotransporter 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC13A2 |
| Gene ID: |
9058 |
| Uniprot ID: |
S13A2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of SLC13A2 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human SLC13A2 |
| Function | Low-affinity sodium-dicarboxylate cotransporter, that mediates the entry of citric acid cycle intermediates, such as succinate, citrate, fumarate and alpha-ketoglutarate (2-oxoglutarate) into the small intestine and renal proximal tubule. Transports the dicarboxylate into the cell with a probable stoichiometry of 3 Na(+) for 1 divalent dicarboxylate, rendering the process electrogenic. Citrate is transported in protonated form as a divalent anion, rather than the trivalent form which is normally found in blood. Has a critical role in renal dicarboxylate transport. |
| Protein Name | Solute Carrier Family 13 Member 2Na(+/Dicarboxylate Cotransporter 1Nadc-1Renal Sodium/Dicarboxylate Cotransporter |
| Database Links | Reactome: R-HSA-433137 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Solute Carrier Family 13 Member 2 antibodyAnti-Na(+/Dicarboxylate Cotransporter 1 antibodyAnti-Nadc-1 antibodyAnti-Renal Sodium/Dicarboxylate Cotransporter antibodyAnti-SLC13A2 antibodyAnti-NADC1 antibodyAnti-SDCT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
