Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Solute carrier family 13 member 2/dicarboxylate cotransporter 1 is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SLC13A2 |
Gene ID: | 9058 |
Uniprot ID: | S13A2_HUMAN |
Specificity: | This antibody detects endogenous levels of SLC13A2 at Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from human SLC13A2 |
Function | Low-affinity sodium-dicarboxylate cotransporter, that mediates the entry of citric acid cycle intermediates, such as succinate, citrate, fumarate and alpha-ketoglutarate (2-oxoglutarate) into the small intestine and renal proximal tubule. Transports the dicarboxylate into the cell with a probable stoichiometry of 3 Na(+) for 1 divalent dicarboxylate, rendering the process electrogenic. Citrate is transported in protonated form as a divalent anion, rather than the trivalent form which is normally found in blood. Has a critical role in renal dicarboxylate transport. |
Protein Name | Solute Carrier Family 13 Member 2 Na(+/Dicarboxylate Cotransporter 1 Nadc-1 Renal Sodium/Dicarboxylate Cotransporter |
Database Links | Reactome: R-HSA-433137 |
Cellular Localisation | Apical Cell Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Solute Carrier Family 13 Member 2 antibody Anti-Na(+/Dicarboxylate Cotransporter 1 antibody Anti-Nadc-1 antibody Anti-Renal Sodium/Dicarboxylate Cotransporter antibody Anti-SLC13A2 antibody Anti-NADC1 antibody Anti-SDCT1 antibody |
Information sourced from Uniprot.org