Anti-SLC13A2 antibody (STJA0007227)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SLC13A2
General Information
| Short Description | Rabbit polyclonal anti-Solute carrier family 13 member 2/dicarboxylate cotransporter 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC13A2 |
| Gene ID | 9058 |
| Uniprot ID | S13A2_HUMAN |
| Immunogen | Synthesized peptide derived from human SLC13A2 |
| Specificity | This antibody detects endogenous levels of SLC13A2 at Human, Mouse, Rat |
Additional Info
| Function | Low-affinity sodium-dicarboxylate cotransporter, that mediates the entry of citric acid cycle intermediates, such as succinate, citrate, fumarate and alpha-ketoglutarate (2-oxoglutarate) into the small intestine and renal proximal tubule. Transports the dicarboxylate into the cell with a probable stoichiometry of 3 Na(+) for 1 divalent dicarboxylate, rendering the process electrogenic. Citrate is transported in protonated form as a divalent anion, rather than the trivalent form which is normally found in blood. Has a critical role in renal dicarboxylate transport. |
| Protein Name | Solute Carrier Family 13 Member 2Na(+/Dicarboxylate Cotransporter 1Nadc-1Renal Sodium/Dicarboxylate Cotransporter |
| Database Links | Reactome: R-HSA-433137 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Solute Carrier Family 13 Member 2 antibodyAnti-Na(+/Dicarboxylate Cotransporter 1 antibodyAnti-Nadc-1 antibodyAnti-Renal Sodium/Dicarboxylate Cotransporter antibodyAnti-SLC13A2 antibodyAnti-NADC1 antibodyAnti-SDCT1 antibody |
Information sourced from Uniprot.org