Host: |
Rabbit |
Applications: |
WB/IHC/IF |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Solute carrier family 12 member 4 (658-708 aa) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:1000-2000IHC 1:100-200IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SLC12A4 |
Gene ID: |
6560 |
Uniprot ID: |
S12A4_HUMAN |
Immunogen Region: |
658-708 aa |
Specificity: |
SLC12A4 protein (A248) detects endogenous levels of SLC12A4 |
Immunogen: |
Synthetic peptide derived from SLC12A4 at the amino acid range 658-708 |
Post Translational Modifications | Phosphorylated, phosphorylation may regulate transporter activity. |
Function | Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia. Isoform 4: No transporter activity. |
Protein Name | Solute Carrier Family 12 Member 4Electroneutral Potassium-Chloride Cotransporter 1Erythroid K-Cl Cotransporter 1Hkcc1 |
Database Links | Reactome: R-HSA-426117 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Solute Carrier Family 12 Member 4 antibodyAnti-Electroneutral Potassium-Chloride Cotransporter 1 antibodyAnti-Erythroid K-Cl Cotransporter 1 antibodyAnti-Hkcc1 antibodyAnti-SLC12A4 antibodyAnti-KCC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance