• Western blot analysis of lysates from 3T3 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-SIMC1 antibody (369-419 aa) (STJ194049)

SKU:
STJ194049

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SUMO-interacting motif-containing protein 1 (369-419 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SIMC1
Gene ID: 375484
Uniprot ID: SIMC1_HUMAN
Immunogen Region: 369-419 aa
Specificity: This antibody detects endogenous levels of CE025 at Human
Immunogen: Synthesized peptide derived from the human CE025 at the amino acid range 369-419
Function Plays a role in SMC5-SMC6 complex recruitment for viral restriction. Forms a complex with SLF2 and this complex is required to recruit SMC5-SMC6 complex to PML nuclear bodies and sites of viral replication. Isoform 1: Inhibits the protease activity of CAPN3. Isoform 5: Inhibits the protease activity of CAPN3.
Protein Name Sumo-Interacting Motif-Containing Protein 1
Platform Element For Inhibition Of Autolytic Degradation
Cellular Localisation Nucleus
Pml Body
Isoform 5: Cytoplasm
Cytoplasm
Myofibril
Sarcomere
Alternative Antibody Names Anti-Sumo-Interacting Motif-Containing Protein 1 antibody
Anti-Platform Element For Inhibition Of Autolytic Degradation antibody
Anti-SIMC1 antibody
Anti-C5orf25 antibody
Anti-PLEIAD antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance