Anti-SIMC1 antibody (369-419 aa) (STJ194049)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human CE025 at the amino acid range 369-419
General Information
| Short Description | Rabbit polyclonal anti-SUMO-interacting motif-containing protein 1 (369-419 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SIMC1 |
| Gene ID | 375484 |
| Uniprot ID | SIMC1_HUMAN |
| Immunogen | Synthesized peptide derived from the human CE025 at the amino acid range 369-419 |
| Immunogen Region | 369-419 aa |
| Specificity | This antibody detects endogenous levels of CE025 at Human |
Additional Info
| Function | Plays a role in SMC5-SMC6 complex recruitment for viral restriction. Forms a complex with SLF2 and this complex is required to recruit SMC5-SMC6 complex to PML nuclear bodies and sites of viral replication. Isoform 1: Inhibits the protease activity of CAPN3. Isoform 5: Inhibits the protease activity of CAPN3. |
| Protein Name | Sumo-Interacting Motif-Containing Protein 1Platform Element For Inhibition Of Autolytic Degradation |
| Database Links | |
| Cellular Localisation | NucleusPml BodyIsoform 5: CytoplasmCytoplasmMyofibrilSarcomere |
| Alternative Antibody Names | Anti-Sumo-Interacting Motif-Containing Protein 1 antibodyAnti-Platform Element For Inhibition Of Autolytic Degradation antibodyAnti-SIMC1 antibodyAnti-C5orf25 antibodyAnti-PLEIAD antibody |
Information sourced from Uniprot.org