Anti-SIL1 antibody (169-219 aa) (STJ195421)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SIL1 at the amino acid range 169-219
General Information
| Short Description | Rabbit polyclonal anti-Nucleotide exchange factor SIL1 (169-219 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SIL1 |
| Gene ID | 64374 |
| Uniprot ID | SIL1_HUMAN |
| Immunogen | Synthesized peptide derived from the human SIL1 at the amino acid range 169-219 |
| Immunogen Region | 169-219 aa |
| Specificity | This antibody detects endogenous levels of SIL1 at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | N-glycosylated. Ubiquitinated by the CRL2(FEM1A) and CRL2(FEM1C) complexes, which recognize the -Lys-Xaa-Xaa-Arg C-degron at the C-terminus, leading to its degradation. |
| Function | Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5. |
| Protein Name | Nucleotide Exchange Factor Sil1Bip-Associated ProteinBap |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Nucleotide Exchange Factor Sil1 antibodyAnti-Bip-Associated Protein antibodyAnti-Bap antibodyAnti-SIL1 antibodyAnti-UNQ545 antibodyAnti-PRO836 antibody |
Information sourced from Uniprot.org