| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Nucleotide exchange factor SIL1 (169-219 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SIL1 |
| Gene ID: | 64374 |
| Uniprot ID: | SIL1_HUMAN |
| Immunogen Region: | 169-219 aa |
| Specificity: | This antibody detects endogenous levels of SIL1 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human SIL1 at the amino acid range 169-219 |
| Post Translational Modifications | N-glycosylated. Ubiquitinated by the CRL2(FEM1A) and CRL2(FEM1C) complexes, which recognize the -Lys-Xaa-Xaa-Arg C-degron at the C-terminus, leading to its degradation. |
| Function | Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5. |
| Protein Name | Nucleotide Exchange Factor Sil1Bip-Associated ProteinBap |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Nucleotide Exchange Factor Sil1 antibodyAnti-Bip-Associated Protein antibodyAnti-Bap antibodyAnti-SIL1 antibodyAnti-UNQ545 antibodyAnti-PRO836 antibody |
Information sourced from Uniprot.org