Anti-SHBG antibody (30-170) (STJ29586)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SHBG (30-170) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:100-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SHBG |
| Gene ID | 6462 |
| Uniprot ID | SHBG_HUMAN |
| Immunogen Region | 30-170 |
| Immunogen Sequence | LRPVLPTQSAHDPPAVHLSN GPGQEPIAVMTFDLTKITKT SSSFEVRTWDPEGVIFYGDT NPKDDWFMLGLRDGRPEIQL HNHWAQLTVGAGPRLDDGRW HQVEVKMEGDSVLLEVDGEE VLRLRQVSGPLTSKRHPIMR I |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 30-170 of human SHBG (NP_001031.2). |
Additional Info
| Tissue Specificity | Isoform 1 and isoform 2 are present in liver and testis. |
| Post Translational Modifications | Variant Asn-356 contains one N-linked (GlcNAc..) at position 356. |
| Function | Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. |
| Protein Name | Sex Hormone-Binding GlobulinShbgSex Steroid-Binding ProteinSbpTestis-Specific Androgen-Binding ProteinAbpTestosterone-Estradiol-Binding GlobulinTebgTestosterone-Estrogen-Binding Globulin |
| Database Links | |
| Cellular Localisation | SecretedIn TestisIt Is Synthesized By The Sertoli CellsSecreted Into The Lumen Of The Seminiferous Tubule And Transported To The Epididymis |
| Alternative Antibody Names | Anti-Sex Hormone-Binding Globulin antibodyAnti-Shbg antibodyAnti-Sex Steroid-Binding Protein antibodyAnti-Sbp antibodyAnti-Testis-Specific Androgen-Binding Protein antibodyAnti-Abp antibodyAnti-Testosterone-Estradiol-Binding Globulin antibodyAnti-Tebg antibodyAnti-Testosterone-Estrogen-Binding Globulin antibodyAnti-SHBG antibody |
Information sourced from Uniprot.org