| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SHBG (30-170) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:100-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SHBG |
| Gene ID: |
6462 |
| Uniprot ID: |
SHBG_HUMAN |
| Immunogen Region: |
30-170 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 30-170 of human SHBG (NP_001031.2). |
| Immunogen Sequence: |
LRPVLPTQSAHDPPAVHLSN GPGQEPIAVMTFDLTKITKT SSSFEVRTWDPEGVIFYGDT NPKDDWFMLGLRDGRPEIQL HNHWAQLTVGAGPRLDDGRW HQVEVKMEGDSVLLEVDGEE VLRLRQVSGPLTSKRHPIMR I |
| Tissue Specificity | Isoform 1 and isoform 2 are present in liver and testis. |
| Post Translational Modifications | Variant Asn-356 contains one N-linked (GlcNAc..) at position 356. |
| Function | Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. |
| Protein Name | Sex Hormone-Binding GlobulinShbgSex Steroid-Binding ProteinSbpTestis-Specific Androgen-Binding ProteinAbpTestosterone-Estradiol-Binding GlobulinTebgTestosterone-Estrogen-Binding Globulin |
| Cellular Localisation | SecretedIn TestisIt Is Synthesized By The Sertoli CellsSecreted Into The Lumen Of The Seminiferous Tubule And Transported To The Epididymis |
| Alternative Antibody Names | Anti-Sex Hormone-Binding Globulin antibodyAnti-Shbg antibodyAnti-Sex Steroid-Binding Protein antibodyAnti-Sbp antibodyAnti-Testis-Specific Androgen-Binding Protein antibodyAnti-Abp antibodyAnti-Testosterone-Estradiol-Binding Globulin antibodyAnti-Tebg antibodyAnti-Testosterone-Estrogen-Binding Globulin antibodyAnti-SHBG antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
