• STJ72539 (0. 1µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SETDB2 antibody (Internal) (STJ72539)

SKU:
STJ72539-100

Shipping:
Free Shipping
Current Stock:
Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-SETDB2 (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.1-0.3µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SETDB2
Gene ID: 83852
Uniprot ID: SETB2_HUMAN
Immunogen Region: Internal
Accession Number: NP_114121.2; NP_001153780.1
Specificity: This antibody is expected to recognize both reported isoforms (NP_114121.2; NP_001153780.1).
Immunogen Sequence: QRRHAKTNSHSSALH
Function Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
Protein Name Histone-Lysine N-Methyltransferase Setdb2
Chronic Lymphocytic Leukemia Deletion Region Gene 8 Protein
Lysine N-Methyltransferase 1f
Set Domain Bifurcated 2
Database Links Reactome: R-HSA-3214841
Cellular Localisation Nucleus
Chromosome
Alternative Antibody Names Anti-Histone-Lysine N-Methyltransferase Setdb2 antibody
Anti-Chronic Lymphocytic Leukemia Deletion Region Gene 8 Protein antibody
Anti-Lysine N-Methyltransferase 1f antibody
Anti-Set Domain Bifurcated 2 antibody
Anti-SETDB2 antibody
Anti-C13orf4 antibody
Anti-CLLD8 antibody
Anti-KMT1F antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance