Anti-SERPINA6/CBG antibody (Internal) (STJ73807)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-SERPINA6/CBG (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:1000.IHC: In paraffin embedded Human Uterus shows brush border staining of endometrial glands. Recommended concentration, 3-6µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINA6 |
| Gene ID | 866 |
| Uniprot ID | CBG_HUMAN |
| Accession Number | NP_001747.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | DLFTNQANFSRIT |
Additional Info
| Post Translational Modifications | N-glycosylated.binds 5 oligosaccharide chains. Glycosylation in position Asn-260 is needed for steroid binding. |
| Function | Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. |
| Protein Name | Corticosteroid-Binding GlobulinCbgSerpin A6Transcortin |
| Database Links | Reactome: R-HSA-194002Reactome: R-HSA-9757110 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Corticosteroid-Binding Globulin antibodyAnti-Cbg antibodyAnti-Serpin A6 antibodyAnti-Transcortin antibodyAnti-SERPINA6 antibodyAnti-CBG antibody |
Information sourced from Uniprot.org