| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SERPINA6/CBG (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:1000.IHC: In paraffin embedded Human Uterus shows brush border staining of endometrial glands. Recommended concentration, 3-6µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SERPINA6 |
| Gene ID: | 866 |
| Uniprot ID: | CBG_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_001747.2 |
| Immunogen Sequence: | DLFTNQANFSRIT |
| Post Translational Modifications | N-glycosylated.binds 5 oligosaccharide chains. Glycosylation in position Asn-260 is needed for steroid binding. |
| Function | Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. |
| Protein Name | Corticosteroid-Binding GlobulinCbgSerpin A6Transcortin |
| Database Links | Reactome: R-HSA-194002Reactome: R-HSA-9757110 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Corticosteroid-Binding Globulin antibodyAnti-Cbg antibodyAnti-Serpin A6 antibodyAnti-Transcortin antibodyAnti-SERPINA6 antibodyAnti-CBG antibody |
Information sourced from Uniprot.org