Anti-SERPINA4 antibody (178-427) (STJ29459)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SERPINA4 (178-427) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINA4 |
| Gene ID | 5267 |
| Uniprot ID | KAIN_HUMAN |
| Immunogen Region | 178-427 |
| Immunogen Sequence | TIQLINDHVKKETRGKIVDL VSELKKDVLMVLVNYIYFKA LWEKPFISSRTTPKDFYVDE NTTVRVPMMLQDQEHHWYLH DRYLPCSVLRMDYKGDATVF FILPNQGKMREIEEVLTPEM LMRWNNLLRKRNFYKKLELH LPKFSISGSYVLDQILPRLG FTDLFSKWADLSGITKQQKL EASKSFHKATLDVDEAGTEA AAATSFAIKFFSAQTNRHIL RFNRPFLVVIFSTSTQSVL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 178-427 of human Kallistatin (SERPINA4) (NP_006206.2). |
Additional Info
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. |
| Protein Name | KallistatinKallikrein InhibitorPeptidase Inhibitor 4Pi-4Serpin A4 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-9925561 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Kallistatin antibodyAnti-Kallikrein Inhibitor antibodyAnti-Peptidase Inhibitor 4 antibodyAnti-Pi-4 antibodyAnti-Serpin A4 antibodyAnti-SERPINA4 antibodyAnti-KST antibodyAnti-PI4 antibody |
Information sourced from Uniprot.org