Anti-SERPINA3 antibody (251-300 aa) (STJ96756)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human SERPINA3 at the amino acid range 251-300
STJ96756
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General Information

Short DescriptionRabbit polyclonal anti-Alpha-1-antichymotrypsin (251-300 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC/IF/ELISA
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolSERPINA3
Gene ID12
Uniprot IDAACT_HUMAN
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human SERPINA3 at the amino acid range 251-300
Immunogen Region251-300 aa
SpecificityAACT Polyclonal Antibody detects endogenous levels of AACT protein.

Additional Info

Post Translational Modifications N- and O-glycosylated.
Function Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.
Protein Name Alpha-1-Antichymotrypsin
Act
Cell Growth-Inhibiting Gene 24/25 Protein
Serpin A3 Cleaved Into - Alpha-1-Antichymotrypsin His-Pro-Less
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-6798695
Cellular Localisation Secreted
Alternative Antibody Names Anti-Alpha-1-Antichymotrypsin antibody
Anti-Act antibody
Anti-Cell Growth-Inhibiting Gene 24/25 Protein antibody
Anti-Serpin A3 Cleaved Into - Alpha-1-Antichymotrypsin His-Pro-Less antibody
Anti-SERPINA3 antibody
Anti-AACT antibody
Anti-GIG24 antibody
Anti-GIG25 antibody

Information sourced from Uniprot.org

Citations

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