| Short Description : | Rabbit polyclonal anti-Alpha-1-antichymotrypsin (251-300 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC-P 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SERPINA3 |
| Gene ID: | 12 |
| Uniprot ID: | AACT_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINA3 at the amino acid range 251-300 |
| Immunogen Region: | 251-300 aa |
| Specificity: | AACT Polyclonal Antibody detects endogenous levels of AACT protein. |
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. |
| Protein Name | Alpha-1-AntichymotrypsinActCell Growth-Inhibiting Gene 24/25 ProteinSerpin A3 Cleaved Into - Alpha-1-Antichymotrypsin His-Pro-Less |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-1-Antichymotrypsin antibodyAnti-Act antibodyAnti-Cell Growth-Inhibiting Gene 24/25 Protein antibodyAnti-Serpin A3 Cleaved Into - Alpha-1-Antichymotrypsin His-Pro-Less antibodyAnti-SERPINA3 antibodyAnti-AACT antibodyAnti-GIG24 antibodyAnti-GIG25 antibody |
Information sourced from Uniprot.org
